Vancouver, BC, Las Vegas, NV – November 2nd, 2023  (CSE: OVAT and OTC: OVATF) – Ovation Science USA Inc. (“Ovation” or the “Company”), with its proprietary topical and transdermal cannabis products powered by its patented skin delivery technology Invisicare®, today announced the signing of an exclusive licensing agreement for Ovation’s topical / transdermal formulations for the state of Missouri. The Company’s new licensee is MidWest Roots, LLC (“MidWest”); a company with a 65,000 square foot cannabis processing facility; one of the largest in Missouri.

Under the terms of the Agreement, MidWest will be responsible for all regulatory, manufacturing, marketing, sales and distribution activities for Ovation’s formulations in the state of Missouri. Ovation will receive royalty income based on wholesale sales to dispensaries. Missouri is approved for adult-use and is growing rapidly, with over 200 dispensaries and already achieving $1.3 billion in sales this year as of the end of August 2023, and according to Headset.io, the sixth largest market. MidWest, known for its expertise in cannabis and consumer goods, is poised to enter the market with Ovation’s products in late Q4 of 2023.

“We are excited to partner with MidWest to bring our innovative topical cannabis products to the Missouri market, said Terry Howlett, President of Ovation. “MidWest has not only a strong production division but also a dynamic team that understands the market including Ovation’s topicals. They have a strong track record of success in the cannabis and consumer goods industry, and we believe that they are the perfect partner to generate revenue in Missouri and bring value for our shareholders.””We are thrilled to bring Ovation’s products to consumers in Missouri. Their products are some of the most effective topical cannabis products on the market, and we believe that they will be a valuable addition to our product line”, said Chris Klein, CEO of Midwest Roots, LLC. “We look forward to launching these products and working with the Ovation team to make it a great success.”

This is the fourth agreement announced by Ovation this year. It follows a recently announced license agreement with Planet 13 for Nevada, a license for Pennsylvania with PA Options for Wellness and a Supply and Distribution Agreement with Golfer’s CBD Ltd. Ovation leverages its expertise in the pharmaceutical industry by using its patented skin delivery technology Invisicare® in its highly effective, proprietary products. Invisicare, backed by over 20 years of research and development, enables substantially more CBD and THC and other cannabinoids to be delivered to and through the skin, which translates into better results for patients. In a recent in-house study, Ovation compared five CBD brand leaders to Ovation Science’s topical CBD cream. All competitor creams tested release less than 2% CBD compared to 40% release from Ovation Science over two hours.

About MidWest Roots, LLC

Midwest Roots has a 65,000 square foot facility for the production of wide variety of cannabis products to serve the Missouri recreational and medical cannabis patients. It is one of the largest facilities in Missouri. Its facility is located in Washington, MO, near Interstates 44 and 70 which makes it an ideal location allowing the company to get the products to dispensaries across the state in a matter of business days. The company produces a variety of cannabis products, including topicals, vape pens, cannabis-infused edibles, pills and (coming soon) pre-rolled joints.

About Ovation Science Inc.

Ovation Science USA Inc, a wholly-owned subsidiary of Ovation Science Inc., is a research and development company that develops topical and transdermal CBD/THC and other cannabinoid products which are out-licensed and also distributed under Ovation’s own brands; ARLO CBD Beauty and InVibe® MD (“wellness” line); all powered by its patented Invisicare® skin delivery technology. Invisicare enhances the delivery of ingredients to and through the skin and is protected by patents and proprietary formulations which cannot be duplicated. With over 20 years of pharmaceutical drug delivery experience, Ovation’s management and science team have created a unique pipeline of over thirty proprietary medical / wellness topical and transdermal products along with a line of anti-aging / beauty formulas. Ovation earns revenues from royalties on licensees’ sales and the sale of Invisicare, along with revenue from its own product sales. Ovation has offices in Vancouver, Canada and Las Vegas, USA.

Stock symbols: CSE under the symbol OVAT and OVATF in the USA on OTC Markets.

Websites: CORPORATE: ovationscience.com

WELLNESS: invibemd.com, BEAUTY: arlocbdbeauty.com

Forward-Looking Statements

Information set forth in this news release contains forward-looking statements that are based on assumptions as of the date of this news release. These statements reflect management’s current estimates, beliefs, intentions and expectations and are subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. In particular there is no assurance of sales and acceptance of its products in any of the state cited, continued sales in dispensaries or in retail markets or expansion to other states. There are no guarantees of future performance or changes to regulations. Ovation Science Inc. cautions that all forward looking statements are inherently uncertain and that actual results may be affected by a number of material factors, many of which are beyond Ovation Science Inc.’s control. Accordingly, readers should not place undue reliance on the forward-looking information. Ovation disclaims any obligation to revise or update any such forward-looking information to reflect future results, events or circumstances, except as required by law.

Neither the Canadian Securities Exchange, OTC Markets nor its Regulation Services Provider accepts responsibility for the adequacy or accuracy of this release.

CORPORATE INQUIRIES:

Doreen McMorran: info@ovationscience.com

PH: PH: 604-982-5700

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

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By Rebecca Olmos | TheCannifornian.com Correspondent

Cannabis topicals are creams, lotions, or oils that can be applied directly to the skin without causing any intoxicating effects. Many people use cannabis-infused topicals to alleviate pain, arthritis, joint issues, and muscle aches. But this study from The Journal of Clinical Investigation found that cannabis may also help with other skin conditions like acne, eczema, and aging.

According to the British Journal of Dermatology, at any given time, a third of the world’s population is dealing with some skin issue. Skin is the body’s largest organ. It is one of the leading medical concerns in all communities, and topicals are one of the fastest-growing categories of cannabis infusion, expected to reach 4.5 billion in sales by 2025, according to a survey by CWI Consulting Services.

So how might cannabis help with your skin?

The two most well-known cannabinoids found in the cannabis plant are tetrahydrocannabinol (THC) and cannabidiol (CBD), both antioxidants. Antioxidants are beneficial for the skin because they protect from free radicals like pollution and UV rays.

THC and CBD are also anti-inflammatories which may be helpful when addressing issues like acne, wrinkles, and psoriasis.

Dispensary or beauty store?

Skincare products are no different than other cannabis-infused products in that they can be cannabis-derived, found in dispensaries, or hemp-derived and found on any health and wellness shelf.

Which one you choose to apply will depend on the issue you’re trying to address and your comfort level. Products higher in CBD might be better for managing any conditions related to inflammation and pain, while THC will be better for skin concerns like wrinkles and dark spots.

Like any new addition to your skincare regime, be mindful of all the ingredients in any product you choose. Start by using a small amount on your skin to see any adverse reactions before committing to a complete application.

By Rebecca Victoria Olmos | TheCannifornian.com Correspondent

What are topicals?

Cannabis is beneficial for our bodies through traditional ingestion methods like smoking or eating and when applied to the body externally through topicals. Topicals are cannabis-infused lotions, creams, oils, or balms that are applied directly to the skin. Since they do not cause any psychoactive effects, they are mainly used in an attempt to help with localized pain, inflammation, and some skin conditions.

How do they work?

Cannabis topicals come in various ratios of cannabinoids like THC and CBD. When applied to the skin, these cannabinoids bind to the cannabinoid receptors in the skin, nerves, and muscles. These receptors are part of an extensive endocannabinoid system that helps to regulate various biological functions throughout the body, like sleep, appetite, pain, and inflammation.

Topicals do not penetrate through the skin to enter the bloodstream, so they do not cause the user any psychoactive effects. It’s important to note because topicals can be confused with transdermals which may cause psychoactive effects. Transdermals contain skin penetrating enhancers that help push the cannabinoids past the epidermis or first layer of skin into the bloodstream.

What might they help?

People have used cannabis-infused topicals for things like arthritis relief, muscle soreness, tension, cramps, psoriasis, eczema, and even headaches. Since cannabis receptors are all over your body, you can even use cannabis topicals for sexual enhancement through infused lubricants.

THC or CBD?

You can be purchase topicals in hemp varieties at health stores or cannabis-derived ones at your nearest dispensary. They will all have different dosages of THC or CBD. Remember that everyone is different and what works for one might not work for you. A good rule of thumb is that if you’re looking for relief from muscle-related issues, steer towards THC-rich products. For joint pain or inflammation, try CBD-rich.

Don’t get discouraged if one product doesn’t work for you. Be open, and experiment with different brands, cannabinoid ratios, and ingredients. And if all else fails, you can always try and make your own infused topical!

With the quickly expanding legal cannabis market finding its legs after years of prohibition, there are several hurdles remaining before the plant and its cannabis-derived product offspring are fully accepted by mainstream society. First and foremost is, of course, full legalization. From that important step everything follows, from banking regulations to changes in incarceration to consumer acceptance. But there is a factor that could serve to speed up the process – scientific research. The more cannabis is proven to be safe and controllable and effective as a medicine, the more likely it is that the powers that be will remove the last remaining barriers to a relatively free market for cannabis products.

In this regard, Ovation Science Inc. (CSE:OVAT) (OTCQB:OVATF) is a leader in the cannabis-derived products sector of the industry. The company has taken its deep pharmaceutical background and focused on developing an advanced, patented, effective, and safe cannabinoid delivery technology called Invisicare®. The system efficiently delivers active ingredients such as THC and CBD in both topical and transdermal applications. To date, Ovation has created over 30 product formulations utilizing Invisicare®. The company has its own consumer product lines Invibe®MD and Arlo CBD Beauty which it sells through its own e-commerce portals while simultaneously licensing their formulations to state operators who then manufacture and market Ovation’s formulations in their designated territory.

We recently interviewed Ovation Science CEO and Co-Founder Terry Howlett about various aspects of the company, its technology, and the market opportunities for Invisicare® products. You can see parts of the conversation here in this article:

Click here to learn more about investing in patented skincare technology

Rooted in Pharmaceutical Science

Ovation’s Head of Product Development, James Roszell, PhD, is a doctoral chemist and leads the team of researchers for the company. He has spent the better part of 20 years developing, testing, refining, and perfecting the Invisicare® technology. He is backed by a Medical Dermatology Advisory Board consisting of dermatology experts based in Canada, the United States, and the United Kingdom. Board members include the former president of the Canadian Dermatology Association, researchers whose work has been published hundreds of times, the editor of a peer-reviewed dermatology journal, and professors at esteemed universities such as Harvard, Yale, University of British Columbia, and the University of Toronto.

The goal of this Advisory Board is to reinforce the science behind its products by providing clinical, scientific, research, and strategic advice to Ovation as it continues to develop and launch Invisicare-based products. It’s a marriage of respected scientists and proven products that is just what the industry needs to achieve further validation with both regulators and consumers alike.

Skincare and Beauty Are Lucrative Markets

Cannabinoids, the active ingredients of cannabis including CBD and THC, are proliferating in topical creams and ointments throughout the world. Applications range from medicinal products meant to address arthritis and chronic pain to beauty creams meant to enhance skin elasticity and health. CBD-infused topicals are expected to reach $4.5 billion in sales by 2025, according to Cultivating Wellness, which represents a 540% increase since 2020.

Invisicare® technology addresses this explosive market by greatly enhancing the delivery of the active ingredients. One major factor issue with traditional topical products is that cannabinoids are hydrophobic – they don’t mix with water very well at all. Human bodies, meanwhile, are famously made of about 60% water. Another issue with topical applications (think sunscreen) is they tend to wear off fairly quickly, meaning that a large percentage of active ingredients don’t penetrate the skin and deliver benefits.

Ovation’s technology ensures much more complete and long lasting delivery for both topical and transdermal applications. The company tested its topical (ingredients to be delivered ON the skin) formulations against a number of leading CBD topicals. The results were staggering, with Invisicare® products demonstrating a 40% active ingredient release rate over a two hour period compared to an average of 3% for the other creams tested. Results were similar for transdermal (ingredients to be delivered THROUGH the skin; like a “patchless patch”) formulas, with Invisicare® providing an 80% penetration rate after six hours compared to 10% to 25% for other products.

What’s Next

Ovation Science is currently investigating partnerships and licensing opportunities with qualified operators in Canada and the United States. Looking to expand on its successful collaboration with its current licensee in Nevada, Ovation’s approach is to develop and produce effective Invisicare® topicals and transdermal cream formulations for licensed operators in key markets across North America and eventually the world. It’s a fairly low overhead, recurring revenue model that allows each company in the partnership to focus on what they do best. Ovation brings the science and expertise, along with its intellectual property protection, while the partner brings distribution, sales, and marketing.

In a young, formerly illegal marketplace like the cannabis industry, scientifically-backed and patented technologies like Invisicare® represent a major step toward broad acceptance. Keep an eye on Ovation Science as it spreads the word about, and the sales of, its innovative products all powered by a breakthrough delivery solution.

Click here to learn more about investing in patented skincare technology

Disclaimer

The above article is sponsored content. CannabisFN.com and CFN Media, have been hired to create awareness. Please follow the link below to view our full disclosure outlining our compensation: http://www.cannabisfn.com/legal-disclaimer/

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

The cannabis industry has been flourishing quite fantastically in recent years. Cannabidiol, or also known as CBD, has also been in limelight due to its list of touted benefits. It is know to be an effective pain reliever and anti-inflammatory product as well as offering many other associated benefits. CBD is a naturally occurring chemical that is found in hemp. Hemp is a type of cannabis plant. CBD has become popular for its therapeutic, medicinal and relaxing qualities that many find helpful. Consequently, it has been growing in popularity in recent years. Trying top quality CBD oil can offer a variety of benefits. For example, it is often used in relieving symptoms associated with inflammation, anxiety, depression, pain, along with other common conditions. It can also be infused into a variety of products such as vaping juices, CBD edibles, oil tinctures, capsules, creams, balms and other products as well.

Here are some ways CBD is commonly consumed:

1. Topical CBD Products

There are a variety of topical CBD products available on the market to choose from nowadays. These topical products such as CBD creams, oils, balms, etc. are one of the most common ways to intake CBD. Some of these products are also regularly used by many athletes. The application of these topical salves, roll-ons, and rubs is a very easy way to administer CBD. They can be applied directly to the skin and they are often used to help in relieving pains and stress as well as for their anti-inflammatory properties. 

Such CBD-infused products can even be found in the beauty salons, pharmacies and other general shopping locations.

2. CBD Tinctures

CBD tinctures are formulations that combine the different ingredients with CBD. Such ingredients may include alcohol or maybe some various flavors to improve the taste. Oftentimes, other dissolving solutions such as vegetable glycerin, ethanol, coconut oil, etc. are also used in creating the CBD-infused tinctures. This type of CBD is consumed with the help of a dropper in a tincture form. Such droppers are used to administer the drops of CBD infused formula below the tongue of the person.

With this method, the human body intakes CBD into the bloodstream very quickly. This is one of the quickest and the simplest method for a person to get their daily dose of CBD. Also, it’s advisable for beginners as it doesn’t involve processes like vaping or smoking for fast results.

3. CBD Vape Pens and Vaporizers

Even though vaping is somewhat similar to smoking, vaporizing is yet another method of consuming CBD. Also, it’s typically thought to be safer than smoking as vaping doesn’t involve combustion. A vaporizer is an atomizer that turns the CBD e-juices into vapors that the consumer inhales. This method is yet another way to consume CBD quickly. The consumer gets a quick and big enough dose of CBD with the inhalation of the vapors that its effects can be more quickly noticeable. But it’s very important to be aware of the type of vaping devices, vape pens and the e-juices that are being used. There are many types of vaping products such as small dab pens for sale on the market. It is important to go to a trusted source. Then you can experiment your way around and decide on what you love best.

4. CBD Oil

The CBD oil and CBD tinctures are pretty similar when it comes to their packaging and application. In fact, they are even produced in somewhat similar manners (i.e. with the CO2 or alcohol extraction). One of the main differences includes is the time of soaking. In this manner, CBD oils are considered to be of better quality than CBD tinctures in comparison. But on the other hand, CBD oils have no flavors to help improve their tastes. As a result, they taste very bitter and that might be a problem for some.

CBD oil can also be consumed by way of vaporizing and there are many vaping devices that use CBD oils. CBD oils have a higher concentration of CBD.

5. CBD Edibles

With the expansion of the cannabis industry, CBD has been incorporated into edible products as well. There are a variety of CBD edibles available in the market such as CBD chocolates, gummies, candies, etc., that all have CBD in them. In fact, nowadays you can easily find many beverages such as CBD teas, milkshakes and other products that have CBD infused in them. So if you want a sweet, tasty and simple way to consume CBD, then you can try out these CBD edible products. In fact, these are the perfect choice for CBD beginners.

In short, there are many fun ways in which you can consume CBD in your daily life. These are convenient, easy and cost friendly.