– Preclinical and early clinical studies of MYMD-1^®, an oral, small-molecule, selective TNF-α inhibitor accepted for presentation –

BALTIMORE, November 17, 2022–(BUSINESS WIRE)–MyMD Pharmaceuticals, Inc.^® (Nasdaq: MYMD) (“MyMD” or “the Company”), a clinical stage biopharmaceutical company developing groundbreaking therapies for the treatment of serious and debilitating autoimmune and inflammatory diseases, has been invited to present late-breaking data at the 2022 British Society for Immunology (BSI) Congress in Liverpool, England.

Late-breaking abstract entitled “Pharmacology and clinical profile of MYMD-1^® (isomyosamine), an oral, selective, next-generation, tumor necrosis factor alpha (TNF-α) inhibitor that crosses the blood brain barrier,” is scheduled for poster presentation on December 6, 2022, at 6pm GMT. In addition to safety and pharmacology data, the presentation will include information on the anti-inflammatory effects of MYMD-1 in a collagen antibody induced arthritis (CAIA) model, which mimics features of arthritis in humans.

“We look forward to presenting these results at BSI and are very pleased that they have been chosen to be shared at this prestigious international gathering of immunology experts,” said Chris Chapman MD, president, director, and chief medical officer at MyMD Pharmaceuticals. “We believe strongly in the potential of MYMD-1 as a next-generation TNF-α inhibitor. With its differentiated oral administration and selectivity, it may one day offer a meaningful therapeutic solution for patients with conditions such as rheumatoid arthritis who are not served by current TNF-α inhibitors.”

MYMD-1 is an oral next-generation TNF-α inhibitor with the potential to transform the way that TNF-α based diseases are treated due to its selectivity and ability to cross the blood brain barrier. MyMD-1 is currently being evaluated in Phase 2 studies for sarcopenia/frailty, a result of the aging process, and has the potential to become the first drug approved by FDA for the condition. MyMD Pharmaceuticals is planning to study MYMD-1^® in early-stage trials for rheumatoid arthritis (RA),

About MYMD-1

MYMD-1, an oral selective inhibitor of tumor necrosis factor-alpha (TNF-α), a driver of chronic inflammation, is being studied to slow the aging process, prevent sarcopenia and frailty, and extend healthy lifespan. MYMD-1 has shown effectiveness in pre-clinical and clinical studies in regulating the immune system. Unlike other therapies, MYMD-1 has been shown in these studies to selectively block TNF-α when it becomes overactivated in autoimmune diseases and cytokine storms, but not block it from doing its normal job of being a first responder to any routine type of moderate infection.

MYMD-1’s ease of oral dosing is another differentiator compared to currently available TNF-α blockers, all of which require delivery by injection or infusion. No FDA-approved TNF inhibitor has ever been dosed orally. In addition, the drug is not immunosuppressive and has not been shown to cause the serious side effects common with traditional therapies that treat inflammation. Because it can cross the blood brain barrier and gain access to the central nervous system (CNS), MYMD-1 is also positioned to be a possible treatment for brain-related disorders. Its mechanism of action and efficacy in diseases including multiple sclerosis (MS) and thyroiditis have been studied through collaborations with several academic institutions.

About MyMD Pharmaceuticals

MyMD Pharmaceuticals, Inc. (Nasdaq: MYMD), is a clinical stage biopharma company developing groundbreaking therapies for the treatment of serious and debilitating autoimmune and inflammatory diseases. MyMD’s lead clinical candidate, MYMD-1^®, is an oral next-generation TNF-α inhibitor with the potential to transform the way TNF-α based diseases are treated due to its small molecule design and selectivity. MYMD-1 has the promise to provide meaningful therapeutic solutions to patients not served by current TNF-α inhibitors and as a potential therapy for CNS-based inflammatory and autoimmune diseases. MYMD-1 has demonstrated the potential to slow the aging process and extend healthy lifespan. The company is evaluating MYMD-1^® in Phase 2 studies for sarcopenia/frailty, a result of the aging process, and is currently planning for early-stage trials for rheumatoid arthritis (RA), with the potential to expand into other applications.

MyMD’s second therapeutic candidate is Supera-CBD, a novel, synthetic, non-toxic cannabidiol (CBD) analog that is 8000 times more potent a CB2 agonist (activator) than plant-based CBD. In addition to its potential role in managing addiction, anxiety, chronic pain and seizures, Supera-CBD has also been shown to have anti-inflammatory effects. For more information, visit www.mymd.com.

Cautionary Statement Regarding Forward-Looking Statements

This press release may contain forward-looking statements. These forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results, performance, or achievements to be materially different from any expected future results, performance, or achievements. Forward-looking statements speak only as of the date they are made and none of MyMD nor its affiliates assume any duty to update forward-looking statements. Words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “may,” “plan,” “will,” “would” and other similar expressions are intended to identify these forward-looking statements. Important factors that could cause actual results to differ materially from those indicated by such forward-looking statements include, without limitation: the timing of, and MyMD’s ability to, obtain and maintain regulatory approvals for clinical trials of MyMD’s pharmaceutical candidates; the timing and results of MyMD’s planned clinical trials for its pharmaceutical candidates; the amount of funds MyMD requires for its pharmaceutical candidates; increased levels of competition; changes in political, economic or regulatory conditions generally and in the markets in which MyMD operates; MyMD’s ability to retain and attract senior management and other key employees; MyMD’s ability to quickly and effectively respond to new technological developments; MyMD’s ability to protect its trade secrets or other proprietary rights, operate without infringing upon the proprietary rights of others and prevent others from infringing on MyMD’s proprietary rights; and the impact of the ongoing COVID-19 pandemic on MyMD’s results of operations, business plan and the global economy. A discussion of these and other factors with respect to MyMD is set forth in the Company’s Annual Report on Form 10-K for the year ended December 31, 2021, filed by MyMD on March 31, 2022, as may be supplemented or amended by the Company’s Quarterly Reports on Form 10-Q. Forward-looking statements speak only as of the date they are made and MyMD disclaims any intention or obligation to revise any forward-looking statements, whether as a result of new information, future events or otherwise.

View source version on businesswire.com: https://www.businesswire.com/news/home/20221117005091/en/

Contacts

Investor Contact:
Robert Schatz
(646) 421-9523
[email protected]

Media Contact:
Andrea Cohen
Sam Brown, Inc.
(917) 209-7163
[email protected]

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

Trial will take place at major U.S. centers and examine the cardioprotective properties of CardiolRx(TM) in patients hospitalized with COVID-19 who have a prior history of, or risk factors for, cardiovascular disease (CVD)

Oakville, Ontario–(Newsfile Corp. – September 25, 2020) – Cardiol Therapeutics Inc. (TSX: CRDL) (OTCQX: CRTPF) (“Cardiol” or the “Company“), a clinical-stage biotechnology company focused on developing innovative therapies for inflammatory heart disease, is pleased to announce that the U.S. Food and Drug Administration (FDA) has approved the Company’s Investigational New Drug (IND) application to commence a Phase II/III, double-blind, placebo-controlled clinical trial investigating the efficacy and safety of CardiolRx, a pharmaceutically produced extra strength cannabidiol formulation, in 422 hospitalized COVID-19 patients with a prior history of, or risk factors for, cardiovascular disease (CVD). The trial will take place at major centers in the United States, where the prevalence of COVID-19 remains high.

Patients with COVID-19 primarily present with respiratory symptoms which can progress to bilateral pneumonia and serious pulmonary complications. It is now recognized that the impact of COVID-19 is not limited to the pulmonary system. Individuals with pre-existing CVD or who have risk factors for CVD (such as diabetes, hypertension, obesity, abnormal serum lipids, or age greater than 64) are at significantly greater risk of developing serious disease from COVID-19 and experience greater morbidity. Moreover, such COVID-19 patients are at significant risk of developing cardiovascular complications (such as acute myocardial infarction, cardiac arrhythmias, myocarditis, stroke, and heart failure) during the course of their illness, and which are frequently fatal, with an estimated 30 – 40% of patients who die from COVID-19 doing so from cardiovascular complications. A strategy to prevent or limit the number or severity of these cardiovascular complications is likely to considerably improve outcomes from this disease.

Cardiol’s Phase II/III trial has been designed to assess the efficacy, safety, and tolerability of CardiolRx in preventing cardiovascular complications in hospitalized patients, with a confirmed diagnosis of COVID-19 within the previous 24 hours, and who have pre-existing CVD and/or significant risk factors for CVD. The composite primary efficacy endpoint will be the difference between the active and placebo groups in the percentage of patients who develop, during the first twenty-eight days following randomization and first dose of study medication, a composite endpoint consisting of one or more of several common outcomes in this patient population, including all-cause mortality, requirement for ICU admission and/or ventilatory support, as well as cardiovascular complications, including the development of heart failure, acute myocardial infarction, myocarditis, stroke, or new sustained or symptomatic arrhythmia.

The study was designed and will be overseen by an independent Steering Committee, consisting of international thought leaders in inflammatory heart disease: Dr. Dennis McNamara (Chair), Professor of Medicine and Director of the Center for Heart Failure Research, University of Pittsburgh; Dr. Leslie Cooper (Co-Chair), Chair of the Mayo Clinic Enterprise Department of Cardiovascular Medicine and Chair of the Department of Cardiovascular Medicine, Mayo Clinic; Dr. Arvind Bhimaraj, Medical Director, Advanced Heart Failure, Mechanical Circulatory Support and Heart Transplant Programs, Houston Methodist Hospital; Dr. Barry Trachtenberg, Director, Cardio-Oncology and Cardiac Amyloid Programs, Associate Director, Mechanical Circulatory Support Program, Houston Methodist Hospital; Dr. Wilson Tang, Director of the Center for Clinical Genomics, Research Director, and staff cardiologist in the Section of Heart Failure and Cardiac Transplantation Medicine, Cleveland Clinic; Dr. Peter Liu, Chief Scientific Officer and Vice President of Research, University of Ottawa Heart Institute; Dr. Carsten Tschöpe, Vice Director of the Dept. of Cardiology, Charité University Medicine Berlin, Germany; and Dr. Matthias Friedrich, Professor of Medicine and Chief, Cardiovascular Imaging, McGill University Health Centre.

Dr. Dennis McNamara, Chair of the Steering Committee for the trial commented: “As a Steering Committee, we are excited about the potential for this study to contribute valuable new information about the role of anti-inflammatory agents in the management of COVID-19. Now that approval from the FDA has been granted, we are anxious to get underway so that we can investigate the impact of CardiolRx in this very important disease process.”

“Receiving approval from the FDA for our IND application to initiate a clinical program in COVID-19 patients represents a major milestone for Cardiol Therapeutics and provides the opportunity to significantly accelerate the commercial development of CardiolRx,” said David Elsley, President and CEO of Cardiol Therapeutics. “The COVID-19 pandemic is providing our Company with a unique opportunity to rapidly study the cardioprotective properties of CardiolRx in patients who have a prior history of, or risk factors for, cardiovascular disease and are most vulnerable to the virus. Subject to study outcomes, our discussions with the FDA indicated that the design and scope of our Phase II/III trial may be used as a registration study in support of a New Drug Application.”

The rationale for using cannabidiol to treat patients with COVID-19 is based on extensive pre-clinical investigations by Cardiol and others in models of cardiovascular inflammation which have demonstrated that CBD has impressive anti-inflammatory and anti-fibrotic activity, as well as anti-ischemic, and anti-arrhythmic action, and that it improves myocardial function in models of heart failure. In pre-clinical models of cardiac injury, cannabidiol was shown to be cardio-protective by reducing cardiac hypertrophy, fibrosis, and the production of certain re-modelling markers, such as cardiac B-type Natriuretic Peptide (BNP), which is typically elevated in patients with heart failure. These data were accepted for presentation at the American College of Cardiology’s 69^th Annual Scientific Session held virtually on March 28 – 30, 2020.

About Cardiol Therapeutics

Cardiol Therapeutics Inc. (TSX: CRDL) (OTCQX: CRTPF) is a clinical-stage biotechnology company focused on developing innovative therapies for inflammatory heart disease. The Company recently received approval from the U.S. FDA for its Investigational New Drug (IND) application to commence a Phase II/III, double-blind, placebo-controlled clinical trial investigating the efficacy and safety of its lead product, CardiolRx, in hospitalized COVID-19 patients with a prior history of, or risk factors for, cardiovascular disease (CVD). CardiolRx is an ultra-pure, high concentration cannabidiol oral formulation that is pharmaceutically produced, manufactured under cGMP, and THC free (<5 ppm).

Cardiol is also planning a Phase II international trial of CardiolRx in acute myocarditis, a condition caused by inflammation in heart tissue, which remains the most common cause of sudden cardiac death in people less than 35 years of age, and developing proprietary cannabidiol formulations for the treatment of chronic heart failure. Chronic heart failure is the leading cause of death and hospitalization in North America, with associated annual healthcare costs in the U.S. alone exceeding $30 billion. For further information about Cardiol Therapeutics, please visit cardiolrx.com.

For further information, please contact:

David Elsley, President & CEO +1-289-910-0850
[email protected]

Trevor Burns, Investor Relations +1-289-910-0855
[email protected]

Cautionary statement regarding forward-looking information:

This news release contains “forward-looking information” within the meaning of applicable Canadian securities laws. All statements, other than statements of historical fact, that address activities, events, or developments that Cardiol Therapeutics Inc. (“Cardiol” or the “Company”) believes, expects, or anticipates will, may, could or might occur in the future are “forward- looking information”. Forward-looking information contained herein may include, but is not limited to, statements with respect to that, subject to study outcomes, our Phase II/III study may be used as a registration study in support of a New Drug Application, the opportunity to significantly accelerate the commercial development of CardiolRx, the Company’s plans for a Phase II international trial of CardiolRx in acute myocarditis, its development of a proprietary cannabidiol formulation for the treatment of chronic heart failure, the potential for this study to contribute valuable new information about the role of anti-inflammatory agents in the management of COVID-19, and the likely improvement of outcomes from COVID-19 resulting from a strategy to prevent or limit the number or severity of cardiovascular complications. Forward-looking information contained herein reflects the current expectations or beliefs of Cardiol based on information currently available to it and is subject to a variety of known and unknown risks and uncertainties and other factors that could cause the actual events or results to differ materially from any future results, performance or achievements expressed or implied by the forward-looking information. These risks and uncertainties and other factors include the risks and uncertainties referred to in the Company’s Annual Information Form dated March 30, 2020, including the risks and uncertainties associated with product commercialization and clinical studies, and uncertainties in predicting treatment outcomes. These risks, uncertainties and other factors should be considered carefully, and investors should not place undue reliance on the forward-looking information. Any forward-looking information speaks only as of the date on which it is made and, except as may be required by applicable securities laws, Cardiol disclaims any intent or obligation to update or revise such forward-looking information, whether as a result of new information, future events or results or otherwise. Although Cardiol believes that the expectations reflected in the forward-looking information are reasonable, they do involve certain assumptions, risks, and uncertainties and are not (and should not be considered to be) guarantees of future performance. It is important that each person reviewing this news release understands the significant risks attendant to the operations of Cardiol.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/64626

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

Cannabidiol, or CBD, is thought to be beneficial for a wide variety of ailments, ranging from poor sleep to pain to PTSD and beyond. To this point, however, there haven’t been many clinical trials conducted to thoroughly prove or disprove the benefits of CBD. So far, it has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of two rare forms of epilepsy in children, as well as for seizures associated with tuberous sclerosis complex. The approved CBD formulation is Epidiolex®, produced and marketed by GW Pharmaceuticals.

Recently, Cardiol Therapeutics Inc. (TSX: CRDL)(OTCQX: CRTPF) announced the initiation of a Phase 1 clinical study, intended to assess the safety, tolerability, and pharmacokinetics of its own CBD formulation, CardiolRx. The results of this study will inform Cardiol’s planned Phase 2 international trial of CardiolRx for the treatment of acute myocarditis, an inflammatory heart condition. The phase 2 trial is being designed in conjunction with heart experts from leading medical centers in the U.S., Canada, and Germany. Rigorous clinical trials are the only way to drug approval, and Cardiol is hopeful that the abundance of laboratory evidence demonstrating CBD’s anti-inflammatory properties translates into clinical proof of efficacy in treating acute myocarditis.

Acute Myocarditis Caused by Viral Infections, Including COVID-19

Cardiol is looking to follow the path blazed by GW Pharma in utilizing the FDA’s Orphan Drug Designation, a program designed to encourage and fast-track development of drugs for the treatment of rare diseases. Acute myocarditis is thought to affect around 70,000 Americans, fitting nicely under the Orphan Drug cap of 200,000 afflicted citizens, and about double the U.S. patient population represented by GW’s treatment for rare childhood epilepsies (Lennox-Gastaut and Dravet Syndromes).

Acute myocarditis is inflammation of the heart muscle, and it most often results from a viral illness such as Coxsackie B, HIV, adenovirus, and hepatitis C. Currently the disease is not easily treatable, if at all, with supportive management of symptoms through the use of steroids being the most common course of action. It is more common in younger adults and can lead to sudden cardiac death in the most severe cases.

As more information is gathered on the effects of the COVID-19 viral infection, it is becoming apparent that a significant number of COVID-19 patients have markers of heart damage consistent with myocarditis, even among those patients demonstrating mild or no symptoms upon diagnosis. Cardiol, already deep into its CBD/heart research, noticed the connection and filed in May for an international patent covering the use of CBD to improve outcomes for COVID-19 patients. The company plans to initiate a clinical program later this year to investigate the potential benefits of CBD in these cases.

CBD as a Drug

Quality control, standardization, and cost effectiveness are among the hurdles facing drug development companies working with plant-based active ingredients. Deriving pure, consistent active ingredients from various batches of plants is difficult and expensive and can be hard to scale when dealing with most any plant. With cannabis, there is the added layer of the plant’s illegal and psychoactive nature. Supply can be constrained, and contaminants like pesticides are often used in producing the crop at scale.

As with historic plant-based drugs like aspirin (from Willow and other species), and the more recent Taxol (from the Pacific Yew), these issues often lead researchers and companies to develop a synthetic or semi-synthetic version of the active ingredient. Cannabis-derived actives are no different.

Cardiol has created, in conjunction with Dalton Pharma Services, its own pharmaceutical CBD product, CardiolRx. Produced in cGMP and FDA-approved facilities, CardiolRx provides consistency and purity in every batch, without the attendant concerns of plant-derived extracts. Production can be scaled without supply chain and quality issues that can make agricultural production difficult. It is an elegant solution to the issues surrounding cannabis-based drug development.

What’s Ahead

As Cardiol Therapeutics conducts its Phase 1 trial, expected to wrap up later this year, the company has a few other irons in the fire. Cardiol is anticipating the imminent launch of a consumer version of its CBD formulation to the medical cannabis market in Canada. Production (with Dalton Pharma) and distribution (with Medical Cannabis by Shoppers Drug Mart) have already been worked out. The company believes it will be the first CBD formulation available in the market that is free of THC (<10 ppm THC), the psychoactive ingredient of cannabis. This feature could be important for patients who want to steer completely clear of any risk of THC interaction.

Cardiol also has two other clinical pathways to explore. There is the aforementioned COVID-19/heart inflammation/CBD trial, as well as a program to investigate CBD as a treatment for heart failure. The company has chosen to focus on acute myocarditis initially, due in large part to the advantages (time and expense) of potential Orphan Drug development. Keep an eye out in the coming months as Cardiol continues to bring its rigorous scientific approach to the world of cannabinoid drug development.

Interested parties are encouraged to listen to Cardiol Therapeutics’ recent presentation at the H.C. Wainwright Virtual 22^nd Annual Global Investment Conference here. Other recent presentations can be found on Cardiol’s website here.

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Robin Lefferts

The COVID-19 outbreak has become a major source of stress over the past several weeks. In addition to the fear and anxiety of disease, quarantines and “stay at home” orders have contributed to stress levels, leading to poor sleep, unhealthy eating, and other side-effects. It’s important for everyone to take inventory of their health and take action.

Let’s take a look at some strategies to cope with these heightened stress and anxiety levels, as well as how cannabidiol (CBD) and adaptogens could play a role.

How to Reduce Stress & Anxiety

There are many different ways to cope with the fear and anxiety stemming from the COVID-19 outbreak. While some people already have good routines in place, others may have to build new habits and integrate them into a completely new lifestyle under lockdown. The good news is that there’s plenty of good advice from the experts.

The Centers for Disease Control (CDC) had several recommendations:

• Take breaks from watching, reading, or listening to news stories, including social media.
• Eat a healthy, well-balanced diet, exercise regularly (away from others), try to get plenty of sleep and avoid smoking cigarettes, alcohol and drugs.
• Connect with others remotely using voice calls or video chats and discuss how you’re feeling and any concerns.
• Take time to yourself and try new activities that you might enjoy.

Other common suggestions include:

• Practice mindfulness by focusing on the present moment from time to time.
• Limit access to stressors by refusing non-essential tasks that are stressful and allowing yourself to take breaks.
• Delegate some responsibilities to others where possible, such as asking children to do the dishes.

While most people have experienced an impact from the crisis, those with pre-existing mental health conditions should be especially cognizant of worsening symptoms. Parents should also monitor the stress levels of children and teens that may experience more intense feelings. Call your healthcare provider if stress gets in the way of your daily activities for several days.

Accredited? Click here to see Innoviom’s deck and learn more about the company’s current offering

CBD & Adaptogens Could Help

There are many different foods and beverages that have a demonstrated ability to promote relaxation and reduced stress levels.

Most people are familiar with the benefits of green tea, chamomile, lavender and lemon balm when it comes to stress reduction. These ingredients are often referred to as adaptogens — or non-toxic plants that help the body resist physical, chemical or biological stressors. Many of them have been used for centuries in Chinese and Ayurvedic healing traditions.

Cannabidiol, or CBD, has also become a popular wellness product over the past several months. In early stage studies, researchers found that CBD may alter serotonin signals that modulate feelings of anxiety and depression. A generalized anxiety disorder study, for instance, showed that CBD reduced stress in animals, such as rats.

Accredited? Click here to see Innoviom’s deck and learn more about the company’s current offering

Innoviom’s goal is to bring these ingredients to consumers through functional beverages. It’s flagship Tranquini® brand is a natural de-stress drink that contains a unique blend of these relaxing adaptogens. Meanwhile, Wowie by Tranquini® combines these adaptogens with hemp extract to provide an even greater relaxation effect.

Unlike other companies, Innoviom has taken the research into adaptogens and CBD and turned it into great tasting functional drinks — with a focus on the great tasting part! Tranquini® is distributed through U.S. chains, such as Meijer, and via distributors, such as KeHE and UNFI. Wowie is also being rolled out in jurisdictions where sales are permitted.

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Looking Ahead

Innoviom is led by CEO Ahmed El Azizi, former Global VP of Functional Beverages at PepsiCo, who has over 20 years of beverage experience. He’s joined by Group CFO Christine Morcos, who came from Pfizer, Gillette and P&G and Chief Growth Officer Julia Trofimova, a former employee of several consumer product companies, including RedBull.

The company’s experienced consumer products team recognized an emerging market opportunity and has the ability to execute on an aggressive growth plan.

Accredited investors interested in learning more about investing in Innoviom can sign up to receive its investor deck and offering details.

Accredited? Click here to see Innoviom’s deck and learn more about the company’s current offering

Statements not evaluated by the FDA.

Innoviom, Inc. Company Contact:

Ahmed Al Azizi CEO

[email protected]

CFN Media Contact:

Frank Lane President

[email protected]

Disclaimer

The above article is sponsored content. CannabisFN.com and CFN Media, have been hired to create awareness. Please follow the link below to view our full disclosure outlining our compensation: http://www.cannabisfn.com/legal-disclaimer/

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

Cannabidiol, better known as CBD, has become one of the most popular wellness products in the United States over the past couple of years. BDS Analytics and Arcview Market Research expect CBD sales to grow at a 49% compound annual growth rate to surpass $20 billion by 2024—making up about half of the total cannabinoid industry—as sales shift from cannabis dispensaries to pharmacy and grocery stores.

CaniBrands brings extensive consumer packaged goods and branding experience to the CBD space, where it has developed a science-based product line encompassing numerous form factors and proprietary formulations. The company’s Can-i products are supported by 12-time Olympic medalist Dara Torres—its Global Spokesperson—and acclaimed high-performance trainer, Andy O’Brien—its Sports Science Advisor.

In a recent interview with CFN Media, Co-Founder and CEO Chris Lords discusses the company’s unique approach to the market and growing product line:

Are you an accredited investor? Learn how to invest in CaniBrands before it goes public

Holistic Approach with Many Choices

CaniBrands offers a premium product line that includes Can-i Boost, Can-i Sleep, Can-i Mend and Can-i Fresh, which are scientifically-formulated to deliver specific wellness benefits.

The company’s best-seller by revenue, Can-i Boost, combines hemp-derived CBD with a powerful blend of vitamins and herbal extracts designed to keep you alert, energized and clear-headed without any crashes or jitters. Meanwhile, the company’s best-seller by volume, Can-i Sleep, combines the same hemp-derived CBD with melatonin and other supplements designed to promote a healthy sleep cycle.

In addition to these best-selling products, the company’s Can-i Mend addresses pain, inflammation and soreness by accelerating the body’s healing process. The product is popular among athletes looking to cut recovery time and reduce post-workout soreness. And finally, the company’s Can-i Fresh is designed to deliver antioxidants, support the immune system and promote mental clarity on a day-to-day basis.

These products are available in multiple form factors, including a sublingual tincture, oral spray and cream, providing customers with many different choices. For example, many athletes appreciate creams to provide localized pain relief, whereas oral sprays provide a convenient on-the-go form factor for busy people. All of these products can be helpful at different times of the day from Can-i Boost in the morning to Can-i Sleep at night.

Are you an accredited investor? Learn how to invest in CaniBrands before it goes public 

Active Expansion into New Markets

CaniBrands has been actively focused on establishing new distribution channels, expanding into new markets and launch new product lines.

The company began by building their own direct-to-consumer platform before moving onto Amazon Prime to access more households. Pilot programs are exploring the possibility of home delivery reselling in local markets, as well as online affiliate marketing, which could significantly expand its distribution and reach new customers throughout the United States that may not otherwise find them online.

Early next year, the company plans to launch its products in Canada before expanding into other international markets. The company’s Brand Ambassador, former NHL player and media personality Paul Bissonnette, will be integral in supporting the Canadian launch. Since becoming the first country to legalize recreational cannabis, Canada has been widely considered a leading market for cannabinoid-based products.

The company also aims to launch a variety of new product lines over time. For example, the company is exploring softgels, beverage, and other product formats (e.g. topicals, bars, and powders), as well as products containing other cannabinoids (e.g. CBN or CBG). The company’s CaniBuy ecommerce management platform also aims to integrate websites, ecommerce, payments and fulfillment into a single client-facing portal.

Gearing Up to Go Public in the Near-term

CaniBrands recently began a $5 million capital raise targeting accredited investors, and the founders and two strategic investors have already committed more than $1 million of the funding round. Management says that the proceeds will be put towards a variety of revenue-driving activities, as well as R&D and general operational expenses.

With no long-term debt, a seasoned management team, commercial products and a solid business model, the company is well-positioned to capitalize on the rapid growth of the CBD market over the coming years.

Accredited investors that are interested in participating in the funding round are encouraged to sign up to receive an investor presentation and corporate updates.

Are you an accredited investor? Learn how to invest in CaniBrands before it goes public

Disclaimer

CannabisFN.com is not an independent financial investment advisor or broker-dealer. You should always consult with your own independent legal, tax, and/or investment professionals before making any investment decisions. The information provided on https://www.cannabisfn.com (the ‘Site’) is either original financial news or paid advertisements drafted by our in-house team or provided by an affiliate. CannabisFN.com, a financial news media and marketing firm enters into media buys or service agreements with the companies that are the subject of the articles posted on the Site or other editorials for advertising such companies.  We are not an independent news media provider. We make no warranty or representation about the information including its completeness, accuracy, truthfulness or reliability and we disclaim, expressly and implicitly, all warranties of any kind, including whether the Information is complete, accurate, truthful, or reliable. As such, your use of the information is at your own risk. Nor do we undertake any obligation to update the items posted. CannabisFN.com received compensation for producing and presenting high quality and sophisticated content on CannabisFN.com along with financial and corporate news.

This article was published by CFN Enterprises Inc. (OTCQB: CNFN), owner and operator of CFN Media, the industry’s leading agency and digital financial media network dedicated to the burgeoning CBD and legal cannabis industries. Call +1 (833) 420-CNFN for more information.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

As an emerging and relatively new line of business, cannabis has already proven itself to be a powerhouse of a market. The global cannabis industry’s revenue ballooned to US $12.2 billion in 2018, with predictions that it will reach $16.9 billion in 2019, according to BDS Analytics.

The burgeoning industry is setting trends in many ways, not the least of which is the role that women are playing across the cannabis landscape. A new report by Vangst surveyed 166 cannabis companies in the US, and found that women represent 38.5% of the employees, a much higher proportion than in other industries, such as tech, construction, and beverage and tobacco.

Of these women, 17.6% held the role of ‘Director’ or ‘Executive.’ 43% of all companies who took part in the survey had a majority of female employees, with seven of these companies being comprised of all-women teams.

For a new industry, this is an exciting trend. Having diversified leadership gives strength to any team, a fact that is illustrated by the culture at The Yield Growth Corp. (CNSX: BOSS) (OTCQB:BOSQF) (Frankfurt:YG3). Headed by CEO Penny Green and a strong team of women leaders, this fresh and innovative company has already had great success in the cannabis industry and, with the continued collaboration of this team of executives, the future looks bright.

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Leaders With Proven Expertise

With over two decades experience building companies, Penny Green is now the Director, President and CEO of The Yield Growth Corp. and CEO of Urban Juve. She has worked in many industries, ranging from music to pharmaceuticals, law to blockchain technology.

Her dossier of public successes is impressive. She was recognised on PROFIT Magazine’s W100 of top Canadian entrepreneurs. Bacchus Law Corporation was in the PROFIT 500 Fastest Growing Companies in 2015 and 2016, when it was under her leadership as CEO. Penny also has substantial experience in capital markets, and has been involved in over 100 private to public companies.

Amy Frankel is another key component of this flourishing company. She is Vice President Licensing & General Counsel to The Yield Growth Corp., and has over 15 years experience in this role building and expanding international brands.

Amy was Co-General Counsel of Aritzia LP (TSX: ATZ). During her time there, annual revenues increased around 100%, jumping from $400 million to $743 million. Amy was also Associate General Counsel of Skechers USA Inc. (NYSE: SKX), where annual revenues increased by approximately 50%. She has expertise in negotiating licensing deals, forming intellectual property strategies and managing international intellectual property portfolios.

Another leader who has a history with Aritzia is Tamara Melck, Chief Operating Officer for The Yield Growth Corp. Tamara has extensive experience in scaling operations. She was a key component in the growth of Aritzia, where she was Vice President, Corporate Operations and Executive Vice President. When she left the company in 2017, it had reached a market capitalization of over US $1 billion. Tamara was also a member and former chair of the Executive Committee of Aritzia.

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Urban Juve’s Impressive Line Up of Leaders

The Urban Juve line is built on ancient Indian Ayurvedic wisdom fused with advanced science, and the leaders at Yield Growth knew they would have to find someone with a commendable background in this discipline. This search led them to Bhavna Solecki.

With over 30 years of Ayurvedic practice, Bhavna is at the centre of Urban Juve’s new generation of products, and oversees its product research, development and production. In 2003, she launched Samadhi Mobile Services, where she led 25 Ayurvedic practitioners on high-profile contracts including George Michael and David Beckham, before developing Inner Evolution Healing Centre Ltd. in 2011 to teach and enable Ayurvedic practitioners.

In 2017, her lifelong experience in Ayurvedic techniques led to the foundation of Urban Juve, alongside Penny Green. As Ayurveda Senior Research Scientist, she ensures compliance with Health Canada regulations, develops educational literature for staff and customers, and incorporates new technology into the supply chain.

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With Bhavna set to oversee the development of Urban Juve products, Yield Growth needed to appoint a President of Urban Juve with a background in the health and beauty industry. Enter Sandi Lesueur, who has designed and launched several product lines for physicians and celebrities, including dermatologist Dr. Jason Rivers and Oprah Winfrey’s makeup artist, Derrick Rutledge at OOH Lifestyle. During her eight year tenure, Sandi played a huge role in the astronomical rise of M.A.C Cosmetics, where she helped the company grow from 3 stores to 88 across Canada.

Sandi also served as CEO of Riversol Skin Care Solutions Inc. where she collaborated with the Vice President of the Dermatology Association of Canada, Dr. Jason Rivers, to develop the company, and founded the second line of Riversol MD.

Her knowledge of the health and wellness industry led her to Urban Juve, where she is now President and on track to position the company as a globally successful brand.

Impressive Public and Investor Relations

Krystal Pineo is the Director of The Yield Growth Corp. She has over eight years experience as an early stage investor and fundraiser for venture capital projects. Krystal founded KP Capital Inc, a family office that invests in early stage startups, and she is also the chief financial officer and director.

Krystal has an impressive global network within the cannabis industry, which led to Urban Juve being included in this year’s pre-Oscar event.

Working alongside Krystal is Kristina Pillon, head of Investor Relations. Kristina joined the Yield Growth Corp. in November 2018. She has an extensive background in public relations and marketing, and nearly 10 years experience in capital markets, where she focussed on small cap metals and mining in a number of roles, including investor relations, marketing, and institutional equity sales. She also has six years experience at Red Cloud Klondike Strike, where she worked in investor relations and institutional equity sales.

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Women Set on Success

Yield Growth is a prime example of the refreshing trend toward diversity throughout the cannabis world. The company is driven by women from a multitude of backgrounds and disciplines, all successful in their own right, and all positioned to take the company to the next level. Keep an eye on this group of women as The Yield Growth Corp. continues to grow its product line and retail footprint across North America and internationally. They mean business, and business is good.

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Disclaimer

CannabisFN.com is not an independent financial investment advisor or broker-dealer. You should always consult with your own independent legal, tax, and/or investment professionals before making any investment decisions. The information provided on https://www.cannabisfn.com(the ‘Site’) is either original financial news or paid advertisements drafted by our in-house team or provided by an affiliate. CannabisFN.com, a financial news media and marketing firm enters into media buys or service agreements with the companies that are the subject of the articles posted on the Site or other editorials for advertising such companies.  We are not an independent news media provider. We make no warranty or representation about the information including its completeness, accuracy, truthfulness or reliability and we disclaim, expressly and implicitly, all warranties of any kind, including whether the Information is complete, accurate, truthful, or reliable. As such, your use of the information is at your own risk. Nor do we undertake any obligation to update the items posted. CannabisFN.com received compensation for producing and presenting high quality and sophisticated content on CannabisFN.com along with financial and corporate news.

About Joy Crosby

Only days after announcing that its wholly owned subsidiary was awarded a German cannabis and cultivation and extraction licence, XPhyto Therapeutics is ready to enter the public domain. With a final prospectus filed with the British Columbia Securities Commission, XPhyto is ready to go public on the CSE under the ticker “XPHY”. The company will begin trading on the CSE on Tuesday, August 6, 2019.

Dual Market Focus: Germany

From its corporate headquarters in Vancouver, XPhyto is developing its business as a leader in formulation, processing, and clinical validation in two of the world’s most active markets, Canada and Germany. Germany, the largest economy in the European Union and second largest federally regulated medical cannabis market in the world (behind the U.S.), is seeing tremendous acceleration in cannabis demand, including importing nearly 2,500 kilograms for medical purposes in the first half of 2019. That’s almost as much as was imported in all of 2018 and more than twice as much as 2017.

Germany Flag on cannabis background. Drug policy. Legalization of marijuana

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Right now, Germany relies 100% on imports to supply is burgeoning medical cannabis market. Based upon some recently issued licenses, it will be until at least late in 2020 before any domestic cannabis will be available for medical purposes.

It is this growth that underscores Arcview Market Research forecasting Germany’s cannabis market to experience a whopping 76.8% compound annual growth rate to reach $1.6 billion by 2022.

Last Wednesday, the Company announced that its wholly owned German subsidiary, Bunker Pflanzenextrakte GmbH, was awarded a cannabis cultivation and extraction licence for scientific purposes from the German Federal Institute for Drugs and Medical Devices, better known as BfArM. Bunker still has to pass BfArM’s security requirements, which isn’t expected to be an issue considering the company operates from a monitored high-security area in Bavaria that previously served as a German air force command center and nuclear bunker.

Bunker has a long-term lease for the entire facility with 10,741 square feet for the initial buildout and nearby space available for expansion.

The new licence authorizes Bunker to cultivate and extract up to 70 different strains of cannabis sativa and indica for scientific R&D.

With the new licence in tow, Bunker is next applying for licenses that will allow for cannabis import, storage, distribution and manufacturing. The license estate is at the heart of Bunker’s plans to serve as a one-stop shop providing a bevy of products and services spanning genetic research and storage, cultivation, extraction, storage, processing, packaging, distribution and more.

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Dual Market Focus: Canada

Canada made history last year when it became the first G7 country to legalize adult-use marijuana. Supply shortages and regulatory challenges kept the industry from getting off to the rip-roaring start analysts expected, but that hasn’t stopped Arcview Market Research and partner BDS Analytics from forecasting the Canadian cannabis market reaching $5.2 billion by 2024.

XPhyto’s operations in Canada are centered on in-house production of pharmaceutical-grade cannabis-derived compounds, developing proprietary formulas and conducting modern clinical research for diseases and conditions with unmet medical need where cannabis could be a viable option. They also offer third-party commercial analytical testing for licensed producers, wholesalers, distributors and law enforcement.

Management is advancing these operations through strategic collaborations that accelerate the process with other collateral benefits. For instance, XPhyto has two five-year agreements with the University of Alberta’s Faculty of Pharmacy and Pharmaceutical Sciences. This partnership provides XPhyto with certified analytical testing capability, as well as a certified extraction, isolation, and formulation facility.

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This is a tremendous capital saver for XPhyto as its cost to entry pales in comparison to the value of the world-class infrastructure, not to mention potential maintenance costs in the future. Furthermore, The University of Alberta is well known for its expertise in biopharmaceutics, drug delivery quality control and regulatory sciences.  An authority like that as a strategic partner gives XPhyto immediate brand recognition as a high quality service provider and access to talent that other companies simply do not easily come by.

Public Soon

XPhyto is hitting the ground running when it comes public as it looks to fill a void between cannabis and modern medical science. They have secured a collaborative partner in the esteemed experts at the University of Alberta to capitalize on the opportunity with minimal capex while the Bunker acquisition – along with its assets – give XPhyto a first mover advantage in the burgeoning German market.

XPhyto will commence trading on the CSE on Tuesday, August 6, 2019, which should have investors keen to participate in the next wave of cannabis opportunities – medical formulations and emerging European markets.

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Disclaimer

CannabisFN.com is not an independent financial investment advisor or broker-dealer. You should always consult with your own independent legal, tax, and/or investment professionals before making any investment decisions. The information provided on https://www.cannabisfn.com (the ‘Site’) is either original financial news or paid advertisements drafted by our in-house team or provided by an affiliate. CannabisFN.com, a financial news media and marketing firm enters into media buys or service agreements with the companies that are the subject of the articles posted on the Site or other editorials for advertising such companies. We are not an independent news media provider. We make no warranty or representation about the information including its completeness, accuracy, truthfulness or reliability and we disclaim, expressly and implicitly, all warranties of any kind, including whether the Information is complete, accurate, truthful, or reliable. As such, your use of the information is at your own risk. Nor do we undertake any obligation to update the items posted. CannabisFN.com received compensation for producing and presenting high quality and sophisticated content on CannabisFN.com along with financial and corporate news.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

The cannabis industry is quickly moving through a well-known cycle for emerging markets. Like Google in the tech industry, early market entrants that have become successful in a given subset of the fragmented market are starting to look to mergers and acquisitions to expand their geographic and product footprint. The result is often a mature industry with two or three companies capturing 70 to 90 percent of the market share.

The most famous example is Canopy Growth Corp.’s (NYSE: CGC) (TSX: WEED) $3.4 billion deal with Acreage Holdings Inc. (CSE: ACRG.U). In exchange for a $300 million upfront commitment, Canopy Growth bought the right to acquire the U.S. market leader when cannabis legalization occurs on a federal level. The combined company could become an overnight leading producer across all of North America.

Let’s take a look at how The Supreme Cannabis Co.’s (TSX: FIRE) (OTCQX: SPRWF) (FRA: 53S1) recent merger with Blissco fits into this same model and what investors can look forward to next.

Expanding into Wellness

Supreme Cannabis’ merger with Blissco was more than a move to increase its revenue and market capitalization—it was a strategic acquisition that accelerates its entry into the lucrative wellness subset of the market with an established brand. Founded in 2013, Blissco has become Canada’s leading cannabis wellness brand with a 12,000 sq. ft., state-of-the-art extraction, processing and cultivation facility located in Vancouver.

Prior to the merger, Blissco was awarded a comprehensive sales license from Health Canada to sell bulk cannabis and pre-packaged, labeled and tested cannabis products to medical patients and provinces. The company had signed supply agreements with British Columbia, Saskatchewan, New Brunswick, and Alberta, as well as Pharmadrug in Germany. It also submitted a license amendment to Health Canada to allow the sale of oil.

Blissco’s focus on ultra-premium cannabis products is well-aligned with Supreme’s similar focus on high-quality flower and pre-rolls, but unlike Supreme, it has been extracting cannabis oil since August of 2018. With its EU GMP-compliant facility, Supreme can immediately leverage its high-quality flower inputs to create near-term, large-scale extraction operations capable of serving multiple brands under its growing umbrella.

Focusing on Growth Ahead

Supreme Cannabis plans to acquire Truverra, a global medical cannabis brand, to further expand its footprint in the wellness space. Located in the Netherlands, Truverra sells a broad portfolio of hemp-based CBD products across select European markets. These products contain a carefully measured quantity of clean and pure CBD oil drawn from whole plant hemp extract that meets European standards.

In order to support this next phase of growth, the company appointed Ash Rajendra as Chief Information Officer and Valerie Rother as vice president of human capital and talent development. Both of these individuals bring a wealth of experience and knowledge necessary to help the company manage these two key acquisitions, as well as pave the way for growth in the nascent cannabis industry.

The company also continues to adopt governance best practices at the board level. Mr. John Fowler resigned from the Board of Directors in order to make room for more independent directors. Mr. Fowler will continue to serve as Chief Advocacy Officer & Managing Director of Flower and Concentrates while the board begins a search for a new independent board member that will bring diverse background, experience and operating knowledge.

Looking Ahead

Supreme Cannabis Co.’s (TSX: FIRE) (OTCQX: SPRWF) (FRA: 53S1) acquisition of two wellness brands marks a move to stake out a key subset of the industry. In addition to adding scale to its operations, the acquisitions provide valuable new brands and extraction capabilities that could help drive long-term shareholder value. Investors interested in the wellness side of the industry may want to take a closer look at the company following these catalysts.

For more information, visit the company’s website at www.supreme.ca.

The above article is sponsored content.

Please follow the link below to view our full disclosure outlining our compensation: https://www.cannabisfn.com/legal-disclaimer.

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

Believe it or not, the world’s first blockbuster drug is still one of the most commonly used today. Acetylsalicylic acid, better known as Aspirin®, is a synthetic derivative of the natural substance salicylic acid, an extract from the bark of the white willow tree. Any company would like to invent a drug that enjoys 100+ years of massive global usage and the possibility exists that cannabis could play a role in making that happen for someone.

Charting a Similar Path

People have been using salicylic acid to treat inflammation and fevers for over 2,400 years.  That’s right, when Greek engineers invented the catapult about 400 B.C., they may have used salicylic acid to treat their achy joints after moving some heavy rocks into position. Later, chemist Charles Frédéric Gerhardt made a breakthrough in 1853 by creating acetylsalicylic acid for the first time.  By 1899, Bayer dialed-in the chemical structure and was selling Aspirin® to the world.

Hemp, a cousin to cannabis that lacks tetrahydrocannabinol (THC), the cannabinoid responsible for the psychoactive high in marijuana, is regarded as one of the world’s oldest industrial crops.  It’s history dates back more than 10,000 years.

About 8,000 years ago, cannabis seeds and oil were used for food in China, with the first documented use of medical cannabis happening by Chinese Emperor Shen Neng roughly 4,750 years ago.  Interestingly, the Chinese world for “anesthesia” (mázui 麻) translates to “cannabis intoxication” because it was used to sedate people (along with wine) before surgery.

Now that the ending of cannabis prohibition is sweeping the globe, there has been a huge upswing in laboratory and clinical research as biotechs and pharmas seek to bring new cannabis-based products to market.  Will one of these drugs become the next aspirin?

Massive Potential

In an interview with Bloomberg, Marc Feldmann, an immunologist who helped discover a class of drugs that includes the blockbusters Humira and Remicade, commented that there is “massive potential” for the medical uses related to cannabis. Dr. Feldman now has dedicated himself to the market opportunity, teaming with cannabis researcher legend Dr. Raphael Mechoulam to start Toronto-based CannBioRex Pharmaceuticals.

While most companies are looking to the cannabis plant for active ingredients, Dr. Feldmann believes that the key to a new class of drugs resides in synthetic cannabis.

Dr. Joseph Tucker, an experienced executive and expert in synthetic active pharmaceutical ingredients (APIs) and drug development and commercialization, shares the view of Dr. Feldmann insomuch that synthetic cannabis represents the future for purity and repeatability in cannabis-based drug development.  Dr. Tucker is the Executive Chair and Co-Founder of Willow Biosciences (CSE: WLLW)(OTC: CANSF) with the purpose of becoming the largest manufacturer of biosynthetically produced cannabinoids.

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The synthetic biology company was formed this year through the merger of BIOCAN Technologies: a team of experienced executives from Calgary and researchers from the University of British Columbia, and Epimeron: a team of researchers from the University of Calgary in Alberta, Canada.

“In addition to consistency and reproducibility, synthetic cannabis can be a much more cost-effective process than plant-based extraction or chemical synthesis, the only options that companies have today,” said Dr. Tucker in a phone interview with CFN Media. “Based on our estimates, biosynthetic production is about 90% faster and cheaper than plant-based extraction. We are of the opinion that synthetic processes will ultimately re-shape how cannabinoids are produced and open new gateways to advanced pharmaceutical opportunities to help people in medical need.”

Willow’s scientific progress is complemented by a team of experts in other areas of business, including CEO Trevor Peters. Peters has co-founded four startups in the last 15 years and been involved in corporate exits totaling more than $4 billion. He was most recently CFO at Caracal Energy, a London listed energy company which Glencore (OTCQX: GLNCY) bought in 2014 for $1.4 billion.

“We’ve got a great, well-rounded team at Willow Biosciences that can execute on our initiatives,” said Dr. Tucker. “There is a growing library of evidence to the effectiveness of cannabinoids.  This will provide tailwinds for drug companies to push hard to utilize cannabinoids in new therapeutics, which should have us well positioned to fill future demand.”

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How Massive is Massive?

Clinically speaking, there are more than 300 cannabidiol (CBD) and other cannabinoid-based treatment options currently in human trials for indications such as PTSD, epilepsy, Parkinson’s disease, chronic pain, schizophrenia and others. The APIs are being sourced from traditional methods, which keeps research on promising rarer cannabinoids out of reach.  In order to tap into this market, an economically viable production method, like synthesis, is necessary.

Historic sales of cannabis-related drugs have been splotchy at best. The market for Marinol (dronabinol), a synthetic pill based on tetrahydrocannabinol (THC) and approved in 1998 for treating nausea and vomiting in cancer patients and anorexia in AIDS patients, was about $150 million in 2016.

On the other hand, analysts are higher on new drugs.  Evaluate Pharma forecasts that Epidiolex, the novel CBD drug of GW Pharma (NASDAQ: GWPH) approved last year by the FDA for treating two rare forms of childhood epilepsy, will reach blockbuster status with sales topping $1 billion in 2021.

More broadly, the U.S. cannabinoid-based pharmaceuticals market size is projected to grow to $50 billion annually by 2029, according to Ackrell Capital’s 2018 Cannabis Investment Report.  Analysts at Cowen predict that U.S. retail sales of CBD will reach $16 billion by 2025.

Willow Biosciences plan is to be a leading player catering to both markets.  In order to achieve this goal, Willow last month partnered with Noramco, the largest supplier of controlled substance APIs in the U.S. and biggest producer of pharmaceutical APIs in the world. Specifically, the two will work collaboratively to develop a yeast-based biosynthesis platform for the production and distribution of CBD.

Noramco is stepping up to tap into this burgeoning market. Per the accord, Willow will take care of expenses related to optimizing the yeast strains and Noramco will take it from there.  Noramco will cover the costs for scale-up, regulatory submission, marketing and distribution through its extensive global network.

The beauty of the deal for a small company like Willow Biosciences is that both partners will share equally in the profits.

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Disclaimer

The above article is sponsored content. Emerging Growth LLC, which owns CannabisFN.com and CFN Media, has been hired to create awareness. Please follow the link below to view our full disclosure outlining our compensation: http://www.cannabisfn.com/legal-disclaimer/

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.

The last six weeks have seen major strides taken by The Yield Growth Corp. (CSE:BOSS) (OTCQB:BOSQF) (Frankfurt:YG3) to maintain their position as an exciting, forward-thinking and innovative cannabis company. An organisation dedicated to disrupting the wellness industry with revolutionary cannabis and hemp-based products, Yield Growth continues to make advances; it has released new products, continued to build and strengthen strategic alliances, and even begun to tackle the global market.

Wright & Well Enters Colorado’s Legal Cannabis Industry

Wright & Well, a subsidiary of Yield Growth, is a bold brand that aims to help relieve pain and anxiety through their line of THC and CBD based oils, gels, balms and other topicals.

On June 20th, the Oregon Liquor Control Commission (OLCC) gave final packaging approval for an additional three cannabis products to be distributed in Oregon. With this in place, Wright & Well will now begin manufacturing on all nine of their products.

According to Statista, legal sales of cannabis in the state of Oregon alone are projected to exceed US $1 billion by 2023, making this a major market to tackle, and an ideal blueprint for the brand as other jurisdictions across the country legalise the sale of cannabis and cannabis based products. Wright & Well jumped into the market early on, and are likely to be an important part of the Yield Growth roster as cannabis trends develop across the country.

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Urban Juve Maintains Notable Position in the Beauty World

Urban Juve is Yield Growth’s flagship brand, which blends ancient Ayurvedic knowledge with cutting edge science and technology to produce a proprietary skincare and wellness line of products, all of which are infused with hemp root and seed oil.

The company recently announced an alliance with beauty giant ipsy, the world’s leading beauty commerce community with over three million monthly members. Part of the alliance included the sale of Urban Juve products on Shopper, ipsy’s exclusive commerce marketplace, and Yield Growth has announced that this is now live.

With the global wellness market worth US $4.2 trillion according to the Global Wellness Institute, analysts now predict that CBD infused products will be a huge part of the industry, with Hemp Industry Daily projecting that within the US, this niche will grow to US $7 billion by 2023. Between their strategic alliances and wide-reaching marketing campaign, Urban Juve has positioned itself to be at the forefront of this new market.

Continuing to Meet Consumer Demands

Urban Juve has seen such positive responses from customers that on July 5th they announced the launch of three new Hemp Daily Ritual Kits, that feature the brand’s most loved products in a curated package.

The kits were launched partly in response to consumer’s who love the products and want to share them with others. ‘Whether personal gifts or professional-volume gifting, our new offering is just what customers are looking for, and our strategic focus on the gift-giving customer helps to generate additional revenue for the brand,” says Sandi Lesueur, president of Urban Juve.

The company continues to identify ways in which to reach new customers, while also maintaining a dedication to their existing customer base.

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Identifying Opportunities for Greater Revenue

Off the success of their existing brands, Yield Growth has invested time and money into the research and production of additional products. On June 25th, the company announced that it has completed testing on nine new products. The products contain hemp and other botanicals and have passed stability and preservation challenge tests at a laboratory in British Columbia.

The nine products include eye cream, deodorant, facial cleansers, facial oils and face masks. All the formulas in Yield Growth’s products are produced with the highest quality essential oils and pure botanical extracts. And in response to growing consumer trends, the company maintains a dedication to cruelty free practices.

With Jefferies financial research group’s estimation that the CBD Beauty Market will reach US $25 billion in ten years and amass 15% of the total skincare industry, Yield Growth is wise to continue to invest in this segment. With plans to launch several brands in California within the next 4 months, Yield Growth continues to prove itself as a force to be reckoned with in the wellness and CBD crossover market.

Going Global: Agreements Underway in Europe

In one of its most exciting reveals, Yield Growth announced on July 2nd that its Urban Juve Anti-Ageing Serum can now be sold in the European market. A Compliance Certificate was issued by Biorius, who is acting as Urban Juve’s Responsible Person in Europe.

Yield Growth had previously signed a letter of intent with Melorganics Hellas, who will act as the exclusive retail distributor and non-exclusive e-commerce distributor for the company’s flagship brand’s products in Cyprus and Greece.

As the European Union continues to create legislation that will bring cannabis closer to the mainstream market, luxury cannabis products such as Urban Juve’s line are becoming increasingly popular. With a population of well over 500 million, the EU offers an enormous market opportunity. Urban Juve hopes to obtain Compliance Certificates for all 11 of its products in the EU, and sales of its products are expected to begin in the fall of this year.

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Positioned to be a Leader as the Industry Develops

Yield Growth is a savvy company which manages to keep its many subsidiaries developing and growing alongside the growth of the industry. It is apt at identifying profitable market opportunities and it seizes these boldly and quickly. This, coupled with the company’s many strategic alliances has positioned Yield Growth to be a leader in the crossover market of cannabis based beauty products, both in North America and globally.

Disclaimer

The above article is sponsored content. Emerging Growth LLC, which owns CannabisFN.com and CFN Media, has been hired to create awareness. Please follow the link below to view our full disclosure outlining our compensation: http://www.cannabisfn.com/legal-disclaimer/

About Ryan Allway

Mr. Allway has over a decade of experience in the financial markets as both a private investor and financial journalist. He has been actively involved in the cannabis industry since its inception, covering public and private companies.